Target definition for shipwreck hunting

Target definition for shipwreck hunting

The research described in the present article was implemented to define the locations of two World War II shipwrecks, the German raider Kormoran, and the Australian light cruiser HMAS Sydney. The paper describes the long and complex trail that led through inefficient oceanographic prediction to ambiguous historical prediction involving a single report and on to precise cognitive prediction base...

The Role of MRSI in Target Volume Definition for Radiation Therapy of Prostate Cancer

Introduction: Recently, magnetic resonance spectroscopic imaging (MRSI), as a functional imaging method, has been used for clinical target volume definition. In this study, we used this method to define the target volume in prostate radiotherapy. Material and Method: In this study, we used images of 20 prostate cancer cases. MRSI and MRI images were fused with CT images. Then, treatment plannin...

Hunting-ton for New Proteases: MMPs as the New Target?

Mutant huntingtin proteolysis mediated by various proteases plays a key role in Huntington's disease (HD) pathogenesis. In this issue of Neuron, Miller et al. have identified 11 proteases, including matrix metalloproteinases (MMPs), that when inhibited reduce huntingtin proteolysis and produce beneficial therapeutic effects. These findings provide new insights into huntingtin proteolysis and it...

Survival after Shipwreck

Elevating Mallarmé’s Shipwreck

This paper discusses collage as a means to explore spatial ideas. It concerns the practice of drawing-as-research, the spatiality of drawing and the nature of paper. It questions the homogeneity of digital tools in contemporary practice. It is introduced with a discussion of architectural representation and space with a historical trajectory. It questions an understanding of space-as-geometry a...